Protocol: Purification of Radiolabeled Oligonucleotides by Precipitation with Cetylpyridinium Bromide Protocol

Radiolabeled nucleic acids, including oligonucleotides, can be separated from unincorporated radiolabel by quantitative, differential precipitation with the cationic detergent cetylpyridinium bromide (CPB).  The nucleic acids are first precipitated from aqueous solution with CPB.

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Protocol: Purification of Radiolabeled Oligonucleotides by Precipitation with Cetylpyridinium Bromide Protocol